ISSN: 1582-5388





Current issue





Public health


National survey of diagnostic x-ray examinations (2000 y)

Cornelia Diaconescu, Olga Iacob

Abstract. The results of the recent survey on the frequency of medical and dental X-ray examinations and of radiation doses received by patients are used to assess population exposure. A total of about 10,555 million medical and dental radiological examinations have been performed in 2000 y (0.49 examination per head of population) resulting an annual per capita effective dose of 0.55 mSv. Compared with that of the last survey (1995), this is 10% lower. However, over the last ten years computed tomography (CT) increased its contribution up to 4.4% of total annual X-ray examinations and still continues; so, the population dose is underestimated without the contribution of CT doses. The much increase of CT and interventional procedures indicates an urgent need to develop activities to estimate and control these high dose procedures, in order to optimize patient and population radiological protection.

Key words: X-ray examinations, annual frequencies, effective dose, type of population dose FULL TEXT.PDF


Trend of chilhood leukaemia in eastern Romania

Doina Davidescu, Cornelia Diaconescu, Ingrid Miron, Doina Georgescu

Abstract. Descriptive epidemiologic analyses were performed in five districts of eastern Romania. The annual incidence rates and the cumulative incidence rates for two equal ten years periods were calculated. Trend was evaluated in linear regression analysis. All childhood leukaemia cases diagnosed between 1992-2001 comparatively with those of 1980-1989 (the control group) in 0-14 years age group have been analyzed. The trend of incidence rates during 1992-2001 was upward. The cumulative incidence rates were significantly increased in 0-4 y. age group (30.8 vs. 18.5; p=0.002) and rural area (25.4 vs. 18.6; p=0.02). The most affected districts were Botoşani (43.1 vs. 14.3; p=0.02) and Vaslui (33.1 vs. 7.98; p=0.02). The majority of cases were acute lymphoblastic leukaemias (69-81%).

Key words: leukaemia, trend, incidence rate, epidemiological study, children FULL TEXT.PDF


Some performance indicators of surgical departments in tertiary hospitals

Odetta Duma

Abstract. The purpose of this study was to assess the performance of twenty surgical units from tertiary hospitals of Iaşi city in 2001 year, through following indicators: average hospital stay and the rates for occupancy, bed turnover and hospital mortality. Interpretation of average hospital stay in surgical care units was based on a comparison of recorded values in different departments with those recommended by Ministry of Health for tertiary hospitals. The highest value compared with that recommended, has been found in a gynecology department (81.8% excess). Seven surgical departments (35 %) exceeded the optimal average hospital stay. High levels of occupancy rates (over 400 days) were found in some departments (general surgery, neurosurgery and orthopedics). Low hospital mortality rates have been found in most surgical departments.

Key words: performance, surgical units, average hospital stay, occupancy rate, bed turnover rate, hospital mortality rate FULL TEXT.PDF


Intoxication death: a ten years survey

Emilia Alexandru Muntianu

Abstract. The aim of the study was to determine the frequency of death intoxication by alcohol and other types of toxic agents as drugs, industrial, carbon monoxide, mushrooms and unidentified ones. 1606 deaths in the eastern part of the country were recorded during 1992-2001. The alcohol was the most frequently toxic agent, which has caused death. There were registered 1347 (83.9%) alcohol intoxication deaths from which 28% were in women and 72% in men. Higher frequencies of death have been found in urban areas (59.8) than in rural ones (40.2). Blood alcohol levels (g) in alcohol intoxications were: 0.5-0.99; 1-1.99; 2-2.99; 3-3.99; 4 and over. The higher frequency of intoxication deaths was found at the level of alcoholemia of 1-3 g (42%), in the groups of age 50-59 years and 40-49 years, both in men and in women. 62 deaths, from which 66% males were caused by a mixture of different toxic agents. There were registered 198 (12.3%) intoxication deaths by the other types of studied agents: drugs, carbon monoxide, industrial agents, mushrooms and unidentified ones. Intoxication deaths caused by these types of toxic agents were more frequently in rural area (53%) and in men (52.5%). The industrial agents were responsible for about 27% of intoxication death, the pesticides being the most frequently (59.8%).

Key words: death, intoxications, alcohol, other toxic agents, environment FULL TEXT.PDF


The effectiveness of MilgammaN therapy in patients with peripheral diabetic neuropathy

Ana Stratone, Carmen Stratone, Roxana Chiruţă, F. Filip, Olimpia Diaconu, Oana Munteanu, F. Topoliceanu

Abstract. Peripheral diabetic neuropathy (PDN) is a severe complication that develops in diabetic patients. Several clinical trials measured the effectiveness of different therapeutical regims for PDN, from which the use of Milgamma-N (Benfotiamine) preparations represents a recent promising option. The paper presents our experience in treating patients with Milgamma-N preparations and assessing the effectiveness of the treatment using a standard paraclinical assessment protocol.

Keywords: diabetes, peripheral neuropathy, Benfotiamine, paraclinical assessment FULL TEXT.PDF


Enamel developmental defects and dental carries frequencies in 8 - 11 y old children

Marinela Păsăreanu, Adriana Nedelcovici

Abstract. The purpose of the study was to compare the dental caries frequencies in children with enamel deficiency, in primary and permanent teeth, in order to show their importance as a health problem. In the studied group the percent of dysplasia of the damaged primary teeth reached a maximum value of 9.1% in ten-year-old girls and 31.4% in boys of the same age. Due to the physiological exfoliation of deciduous teeth, the proportion decreased to 0 near the age of 11 y. At the permanent teeth, a change of the pattern diseases appeared because the age of 8-11 is the period of mixed dentition. The eruption of permanent teeth being in progress, the cavities at these teeth are less and the weight of dental dysplasia is higher within the total number of damaged teeth.

Key words: primary and permanent dentition, caries, defects of enamel development FULL TEXT.PDF


Epidemiology: communicable diseases


Ceftriaxone resistance in Streptococcus pneumoniae isolated from pediatric infections

Gabriela Coman, Elena Petraru, Roxana Filip, Cătălina Dahorea, F. Butnaru

Abstract. Streptococcus pneumoniae- major cause of infection in children - causes serious therapeutic difficulties, because of the developed multiresistance. Extended-spectrum cephalosporins, used in empirical therapy are a therapeutic option. Recent emergence of Ceftriaxone (CRO) and Cefotaxime (CTX) resistant strains with regional differences in frequency requires their detection by quantitative determinations. The results of the first study on children from Iasi concerning CRO resistance of S. pneumoniae, evaluated according to NCCLS 2002 criteria, showed the presence of this phenotype in ear and lower respiratory tract infections. Authors recommend quantitative testing for CRO of high level P resistant strains, isolated from these infections, when CRO is a therapeutic option and surveillance of occurrence of this resistance phenotype in strains isolated from non respiratory infections.

Keywords: Streptococcus pneumoniae, ceftriaxone resistance, revision breakpoints FULL TEXT.PDF


Escherichia coli enterohemoragic an emerged pathogen of human infections Part II. Non-O157 Escherichia coli enterohemorrhagic

Sofia Constantiniu

Abstract. The incidence of the non-O157 enterohemorrhagic Escherichia coli (EHEC) - non-O157:H7 Shiga toxin-producing E. coli (STEC) infections increased in the last years. Many serotypes of this toxigenic E.coli group were isolated from hemolytic uremic syndrome (HUS) and hemorrhagic colitis (HC) cases. The STEC strains possess many virulence factors codified by plasmids. Among the over 200 non-O157 STEC serotypes, more than 100 serotypes have been associated with HC or HUS in humans. The serogroups O26, O103, O111 and O145 are most commonly isolated from humans and are clearly recognized as human pathogens. STEC can be found in the fecal flora of a variety of animals. Domestic cattle and other ruminants constitute a natural reservoir for STEC. Usually STEC are transmitted to humans by food, water and from person to person. Foods, particularly foods of animal origin, the beef meat, represent a major vehicle of transmission of non-O157 STEC. The detection of the STEC is possible by many systems: Stx-specific PCR, Vero cell toxicity test, Enterohemolysin-agar, Stx-EIA on direct stool, Stx-EIA on stool culture grown overnight in TSB. Serological diagnosis is also possible. Antibodies to Stx or LPS have been proposed as markers of recent infection.

Key-words: non-O157:H7 Shiga toxin-producing Escherichia coli (STEC), infection, serotype, source, laboratory diagnosis, EHEC FULL TEXT.PDF