†††††††††††††††††††††††††††††††††††† C O N T E N T S
Odetta Duma, Laura Munteanu †
Abstract. University hospitals provide the highest level of medical care available for less frequent and very complicated conditions and instances of last referral care. The largest share of national health expenditure gets for hospitals, regardless of the health status and income level of a population. Within the hospital sector, the university hospitals after a negotiation of their budget with insurance houses generally get a big part of the available financial resources. In addition, a significant part of the other essential health sector resources like human, physical or technological are usually concentrated in these hospitals. The goal of the present study was to assess the supply of specialized services in a university hospital based on utilization pattern of existing resources. The concept of allocative efficiency has been used. Analysis was based on indicators, which are relevant for hospital activity: average hospital stay, bed turnover rate, occupancy rate, hospital mortality.
Marieta Vasilov, Gabriela Mancaş, Gabriela Albu, Carmen Hura, Maria Brădăţan†††††††† †
Abstract. The authors
present a synthesis of nine epidemiological studies performed in the interval
1988-2000 in areas with a long term-exposure to nitrogenous compounds,
pollutants of environment (drinking water and food products). 1488 children
(0-3 years) from five districts in eastern
Elena Lungu, Iliana Palamaru, Lidia Rusu †
Abstract. The main objective of this survey was to evaluate
if there are gender differences among patients diagnosed with primary
hypertension. Two catchment areas in
Ana Ţarcă, C. Barabolski †
Abstract. Palmary dermatoglyphics, of a group of 102 epilepsy-stricken children and teenagers (51 boys and 51 girls), with ages between 2 and 17 years, have been analyzed. Some significant distortions, inducing deep clinical implications, which differentiate the patients from the apparently normal population, have been found. Some of the palmary dermatoglyphic anomalies, occurring in high ratios with both boys and - especially - girls, predominantly on the left palms of the subjects (equally boys and girls), have also been observed at other European groups of epileptics. The papillary ridgesí disposition as a dense and very dense network at the Thenar/I level, and the finalization of line Tís direction in palmís field 11 and 12 - instead of 13 -, as we found, contribute to enriching the indicators of epilepsyís dermatoglyphic diagnosis - at least for the patients met in Moldavia, for which reference data had been provided.
Key words: epilepsy, dermatoglyphic diagnosis, children, teenagers†† ‹ FULL TEXT.PDF
Luminiţa Jerca, Oltiţa Jerca, Gabriela Mancaş, Irina Constantinescu, R.Lupuşoru †
Abstract. Nitric oxide (NO∑) synthesized in endothelial cells, from the terminal guanidino nitrogen atom of L-ARG, by means of NO-synthase (NOS), activates guanylyl-cyclase in smooth muscle cells and plateletes, increasing the levels of the intracellular messenger cyclic guanylyl phosphate (GMPc). This phenomens produces smooth muscle relaxation and platelet aggregation inhibition, presumably by reduction of the intracellular free Ca2+ concentration. The endothelial vasodilator prostacyclin causes the same effects through adenylyl-cyclase activation, which increases intracellular level of AMPc. The biological activity of NO∑ may be modified by oxygen-derived reactive species, such as anion superoxide (O2), hydrogen peroxide (H2O2) and hydroxyl radical (OH∑), contributing to regulate the vascular tone. NO∑ may posses both cytoprotective and cytotoxic properties, depending on the amount and the isoform of NOS. NO∑ may regulate hepatic metabolism directly by causing alterations in hepatocellular metabolism and function, or indirectly as a result of its vasodilator properties.
V.C. Tomulescu, Raluca Gheorghe, Olga Iacob
Abstract. A high level of radon daughters concentration has a tremendous impact on the effective dose received by the workers. This paper presents the annual effective doses received by different Reference Workers performing different type of activity in uranium mines. The effect of mitigation is presented as a comparison of the annual dose levels for equilibrium and for non-equilibrium conditions between radon and its short-lived decay daughters.
Key words: radon daughters, Reference Worker, annual effective dose† ‹ FULL TEXT.PDF
Irina Anca Popescu, Doina Popa, Doina Hăv‚rneanu, T. Ghindaru, Irina Alexandrescu †
Abstract. Our study aimed the early detection of respiratory injuries afflicted with occupational exposure to chromium, cadmium, nickel and their compounds, with a known high carcinogenic risk. 23 platers (average of exposure 15.57Ī5.05 years) and matched controls have been investigated by clinical examination (including otolaryngology exam) completed by sputum cytology and an individual questionnaire.
Heavy metals concentration, as well as the microclimate factors, were measured in working area and revealed the values near to the admitted limits. Sputum investigations found the type I cytology in 37.8% of workers vs. 82.6% of controls, type II cytology in 43.5% vs.17.4%, respectively. Two workers had sputum cytology of III type, with nucleolar alterations and suspected tumor cells. At 60.8% of people in exposed group were identified ferruginous bodies, in all types of sputum cytology, comparatively with only one case in control group. 74% of platers had chronic upper respiratory diseases vs. 26.1% of controls; 56.5% had pulmonary emphysema vs. 0% in control group. Plating industry is responsible for chronic respiratory diseases, with possible malignancy risk, even the concentrations of heavy metals in the air are in admitted limits.
Precancerous injuries can be seen by sputum cytology a simple, noninvasive, and not expansive method, requiring a carefully monitoring of workers. The presence, in a high proportion, of ferruginous bodies, unspecific to heavy metals exposure, entails revaluation of the exposure in working place.
Epidemiology: communicable disease
Abstract. One of several Shiga toxin-producing serotypes of Escherichia coli is O157 serotype. E.coli O157 was first identified as a human pathogen in 1982 and then has involved from a clinical novelty to a worldwide public health concern. This organism known to cause human illnesses develops from mild non-bloody diarrhoea to haemorrhagic colitis, haemolytic uremic syndrome and death. The bacterium evolved through acquisition of genes for Shiga toxin and many other virulence factors. The cattle and many other animal species represent the reservoir for human infection with E.coli O157. This serotype is transmitted by food, water and directly from one person to another. There are different laboratory methods for isolation and identification of E.coli O157. Surveillance, rapid reporting of cases and ready epidemiologic investigations are essential elements of timely public health response.
Irina Popovici, Didona Ungureanu, Cătălina Elena Lupuşoru