ISSN: 1582-5388





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Public health


Natural radioactivity of some mineral waters and population doses

Elena Botezatu, Olga Iacob, Angela Aflorei, Garofiţa Elisei, Olga Căpitanu

Abstract. There are many mineral water springs in the northeastern Romania which, traditionally, are used as table mineral water sources in the area. This study has as basic objectives the radioactivity control of the drinking mineral waters according to existing standards and evaluation of doses to population by ingestion of mineral water. During the period from 1997 to 2000, 107 water samples (bottled waters commercially available for human intake and some spring waters) were collected. Their total alpha and beta radioactivity and the natural radioelements (natural uranium and thorium, radium-226 and potassium-40) were measured. The following contents were found: 0.25 35 mBq/l for 238U; 0.04 4.4 mBq/l for 232Th and 9 1250 mBq/l for 40K. The corresponding activities of 226Ra up to 1 Bq/l and concentrations of gross alpha radioactivity up to 3 Bq/l were also measured. The values obtained were compared with the reference ones accepted for drinking water. A calculation of dose based on radioactive content data and the ICRP (International Commission on Radiological Protection) dozimetric model for ingestion was performed. The effective dose values due to the intake of these radioelements through water consumption were estimated to range from about 1.5 to 28 μSv/y. The resulting individual annual effective doses are very low quite insignificantly versus other natural sources. The contribution of mineral water to overall exposure from natural sources is only of 0.25 % up to 1.2 %.

Key words: mineral water, springs, bottled water, natural radioactivity, gross alpha and beta radioactivity, specific activities of natural uranium, natural thorium, radium-226, potassium-40, effective doses FULL TEXT.PDF


Physical development of child and adolescent: results of the 1999 survey

Marieta Vasilov, Oana Drug, Lidia Rusu, L. Abiţei, Maria Barbu, A. Chiroşcă, Luminiţa Manole, Brnduşa Seciu, Petronela Simion, Angela Verban

Abstract. In 1999 a study on physical development of children between 0-18 years of age was performed. Present investigation is a 8th stage of the national study which begun in 1950. The authors present the results of physical examination of over 53,000 children and adolescents living in 7 districts from the eastern Romania: the average levels of the anthropometrical indices by age, gender, residence area, the distribution by physical development, comparative aspects with previous stage made in 1992. The paper conclusions discuss the opportunity to continue this longitudinal study with its limits and value and recommendation in order to improve the methodology for the subsequent stages.

Key words: child, adolescent, physical development indices, loco-regional developmental standards, longitudinal study, trend of physical development FULL TEXT.PDF


Maternal haematological and biochemical parameters and pregnancy outcome

Victoria Papadopol, Otilia Damian, Iliana Palamaru, Cristina Adam, Nicoleta Florescu, Doina Dămăceanu

Abstract. An important external risk factor for pregnant women and newborn health is unbalanced nutrition of pregnant women. We have examined how some parameters reflecting nutritional status of a group of mothers delivering are related to the pregnancy outcome. The studied group consisted of 211 fullterm pregnant women who were hospitalized for delivery in Cuza Vodă Maternity from Iaşi. Haemoglobin, haematocrit and erythrocyte count were determined as well as glucose, total proteins, albumin, triglycerides and cholesterol levels. The pregnancy outcome included: duration of gestation, foetal length, birthweight, 5 min Apgar score and head circumference. Laboratory tests showed a low maternal mean level of haemoglobin which emphasizes, beside other factors, an unsatisfactory nutritional status. Mean values of newborns indices were in normal limits. Of the investigated mother parameters, haemoglobin showed positive correlations with newborn length while total protein showed negative correlation with weight.

Key words: pregnancy, maternal haematological and biochemical parameters, newborn data FULL TEXT.PDF


Dyslipidemia in hypertensive patients in a primary care unit catchment area

Elena Lungu, Iliana Palamaru, Lidia Rusu, Roxana Alexandrescu

Abstracts. The present study is part of a program with aimed to assess the prevalence of physical, metabolic and behavioural risk factors related to primary hypertension. This cross-sectional survey was conducted in a primary care unit in Iasi city between 1997 and 1999. The mean age of investigated persons was 53.99.8 years for the I-st hypertension grade of severity, 62.210.6 for the II-nd hypertension grade of severity, 67.3 11.2 years for the III-rd hypertension grade of severity and 55.99.0 years for the IV-th hypertension grade of severity. Body mass index (BMI) had average values between 26.56.1 and 30.14.1 kg/m2, indicating a moderate risk for cardiovascular disease. According to family history 36% of patients had a hypertensiv history (father and mother). Serum total/HDL cholesterol ratio was higher than 5 in 12% of cases, indicating an atherogenic risk.

Key words: primary hypertension, body mass index, HDL-cholesterol, LDL-cholesterol, cardiovascular disease. FULL TEXT.PDF


A follow-up of men and women who grew up in Romanian orphanages

N. Lie, D. Murarasu

Abstract. In 1997-98, 55 boys (born 1976) and 20 girls (born 1977) who grew up in Romania orphanages were followed up. 31% of the men and 24% of the women had good contact with their families, whereas 40% of the men and 58% of the women had no contact at all. Only 15% of the men and 29% of the women were in school or had a legal job, while 27% of the men and 35% of the women had never had a job at all. The majority had lived partly in places not intended for human habitation, and partly by foundations, friends, occasional employers and in hostels of schools and factories. Only 32% had rented accommodation, while 11% were exclusively street youths. Poor physical health was reported by 3% of the men and 24% of the women, whereas 45% of the men and 24% of the women had some minor medical problems. Serious mental disorder was present in 7%, and 16% had some mental problems. None admitted alcohol abuse, but 7% of the men reported some problems with drinking. Most had probably committed minor crimes without being arrested. Of 14 men with files in the criminal register, 12 (22%) had been sentenced to imprisonment. Only 26% of both sexes were satisfied with themselves, and only35% of the men and 25% of the women were satisfied with their lives. Ten of 20 women had given birth to one each. Of 10 children, one died shortly after birth, and five are living in orphanages.

Key words: orphanages, ex-care, follow-up, jobs, accommodation, diseases, alcohol, drugs, criminality FULL TEXT.PDF


Epidemiology: communicable diseases


The development of human papilloma virus (HPV) vaccines

Mihaela Grigore, Ana Cristina Anton

Abstract. The discovery that human papilloma virus (HPV) causes the vast majority of cervical cancers opens new possibilities for controlling this disease, which is the second most common cancer among women worldwide. Research centers around the world are actively involved in developing HPV vaccines. The paper presents the latest information regarding both prophylactic and therapeutic vaccines.

Key words: human papiloma virus, vaccine, cervical cancer FULL TEXT.PDF


Humoral immune response of hospital employees induced by a recombinant hepatitis b vaccine: 5 years after the primary standard immunization

E.Platkov, E.Shlyakhov, V.Glick, S.Khalemsky, A.Fischbein

Abstract. 148 hospital employees were examined at different time periods after immunization with recombinant DNA Hepatitis B vaccine (Engerix-B) according to recommended intramuscular method. 20 (13.5%) hospital employees for whom 5 years have elapsed since first vaccination had insufficient levels of antibody (HBsAb) response, <10 mIU/ml, and considered unprotected. 46 (31.1%) had titers between 11 and 100 mIU/ml indicating feeble protection. 82 (55.4%) were considered sufficiently protected (>100 mIU/ml), and 28 (18.9%) from them had very high levels of HBsAb (>1000 mIU/ml). HBsAg was not detected in any of examined workers. Median concentrations of serum immunoglobulins (IgG, IgM, IgA) were within normal laboratory ranges, but lower among unprotected and feebly protected persons than among those with sufficient protection. Our data demonstrate an association of time lapse between vaccination and the degree of antibody response. They also suggest that immunological host factors influence the outcome of vaccination.

Key words: hepatitis B vaccination, hospital employees, and humoral response FULL TEXT.PDF


Setotypes of escherichia coli enteroinvasive in northeastern districts of Romania

Sofia Constantiniu, I.Buzdugan, Angela Romaniuc, L. Cozma, Raluca Filimon, Mariana Dumbrava, Anca Nistor, Lucia Teodoru, Paraschiva Onu, Gabriela Danis

Abstract. 30 E.coli enteroinvasive (EIEC) strains were studied concerning their biochemical characteristics, antigenic behaviour and the pathogenicity in vivo and in vitro. The strains were isolated from children with acute diarrhoea and patients of a foodborne outbreak . All strains presented the general biochemical reactions of the Escherichia genus and some characteristics resembling with Shigella genus nonmotile, fermentation of glucose whithout gas production, negative for lysine decarboxilase.

According to slide and in tubes agglutination tests the strains were included in the following serotypes: O25 , O28, O42 , O112 , O124 , O136 , O142 , O144.

From 34 strains which agglutinated with anti EIEC monovalent sera only 30 (85.7%) had the ability to produce keratoconjunctivitis on guinea pigs eye. On Congo red agar all EIEC strains were unpigmented. It is not a correlation between the capacity to bind the dye and the pathogenicity of EIEC strains.

Key-words: E.coli, enteroinvasive, biochemical characteristic, serotype, pathogenicity FULL TEXT.PDF


History of medicine


Practical activities in public health field in a model rural center before the 2nd world war

Cristina Ionescu

Inspired by the progressive ideas of preventive medicine, the model health rural units, although able to solve the public health problems only in restricted areas, were like true light spots on the country map, demonstrating that an appropriate health care organization eventually lead to a significant decrease of morbidity and mortality rates. The Health Center from Tomeşti was one of the three model rural units of preventive medicine organized by the Ministry of Health to be affiliated to one of the existing Institutes of Public Health: Iaşi, Cluj and Bucureşti respectively. The center was coordinated by Prof. Al. Slătineanu as Director of the Iasi Institute of Hygiene and Public Health and Prof. Dr. Alexa, departmental supervisor. FULL TEXT.PDF